The present invention relates to a system and methodology to enable efficient storage and handling of hand held devices and conveniently provide access to information within the devices. Single-handed storage and removal features enable users to insert and remove the device into and from a multifunctional cradle. The cradle mitigates device damage by limiting device movement and/or vibration once accepted into the cradle. One or more auxiliary storage compartments that feature single-handed component storage and removal can be included with the cradle. Functional segmentation of the cradle enables interface components within the cradle to be isolated from regions that can be exposed to contamination. The cradle includes operative connections for devices stored in the cradle to facilitate operations, such as charging the device and exchanging or updating device information with other local and/or remote systems.