An embodiment of a non-invasive RF system for inducing hyperthermia in a target area, and a corresponding non-invasive RF method for inducing hyperthermia in a target area are provided. The system includes an RF transmitter and transmission head, and RF receiver and reception head wherein the transmission and reception heads are arranged proximate a target area so that an RF signal between the heads induces hyperthermia in the target area. The method includes arranging the transmission head and reception head proximate and on either side of a target area and transmitting an RF signal through the target area.