A method for treating subjects with abnormal cell proliferation is provided. The method involves administering to subjects in need of such treatment an effective amount of an agent of Formula I, to inhibit cell proliferation such as that associated with tumor growth and metastasis. A method for inhibiting angiogenesis in an abnormal proliferative cell mass by the administration of an agent of Formula I is also provided.

 
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> Detection of nucleic acid heteroduplex molecules by anion-exchange chromatography

> Polynucleotide encoding a human receptor tyrosine kinase

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