Antisense compounds, compositions and methods are provided for modulating the expression of sterol regulatory element-binding protein-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sterol regulatory element-binding protein-1. Methods of using these compounds for modulation of sterol regulatory element-binding protein-1 expression and for treatment of diseases associated with expression of sterol regulatory element-binding protein-1 are provided.

 
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< HIF oligonucleotide decoy molecules

< Plant centromere compositions

> Design and therapeutic use of adpase enhanced apyrases

> Modulation of tyrosinase expression

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