Compounds, compositions, and methods are provided for treatment of disorders related to mitochondrial dysfunction. The methods comprise administering to a mammal a composition containing pyrimidine nucleotide precursors in amounts sufficient to treat symptoms resulting from mitochondrial respiratory chain deficiencies.

 
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< Uridine administration improves phosphatide synthesis, synaptic transmission and cogntive function

< Prodrug, medicinal utilization thereof and process for producing the same

> Combination therapy with inhibitors of inducible nitric oxide synthase and alkylating agents

> Protease inhibitors
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