Compounds of the formula (I): wherein R1, R2, R3,
p, q, and X are as defined within and a pharmaceutically acceptable salts and in
vivo hydrolysable esters are described. Also described are processes for their
preparation and their use as medicaments, particularly medicaments for producing
a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal,
such as man.
##STR1##
