A process of making an osteopathy solution includes the steps of (a) soaking a raw composition which includes Radix Angelicae Sinensis, Radix Paeoniae Rubra, Rhizoma seu Radix Notopterygii, Radix Angelicae Dahuricae, Herba Asari, Folium Artemisiae Argyi, Radix Angelicae Pubescentis, Radix Dipsaci, Myrrha, Ramulus Mori, Radix Rubiae, Radix Clematidis, Radix Stephaniae Tetrandrae, Rhizoma Cimicifugae and Radix Gentianae Macrophyllae in a predetermined amount of water for a predetermined period of soaking time to form a pre-decocting solution and a pre-decocting composition; (b) heating the pre-decocting solution and the pre-decocting composition for a predetermined period of reaction time to form a mixture consisting of a residual composition and a solution; wherein a volume ratio of said solution in step (b) and said water in step (a) is approximately 1:3; and (c) cooling down the solution to a predetermined temperature.