The invention relates generally to systems and methods for processing radiographic and other medical-related images (collectively "imaging system" or simply the "system"). More specifically, the invention relates to a system for associating particular calibration information with a particular radiographic image. Calibrated images processed by the system can be created from radiographic images and calibration information associated with the radiographic images. In many embodiments, the system includes a user interface that automatically configures itself in accordance with the calibration information embedded with the radiographic image. The system can include a user interface configured to obtain the calibration from the data object.