The present invention provides isotopically labeled oxazinocarbazole derivatives having a ring connecting position 8 (C-8) and position 9 (N-9), and more specifically, provides compounds of formula (I) wherein R1, R2, R3 and R4 are described herein. ##STR1## These compounds are useful in the diagnostic analysis of diseases wherein modulation of 5-HT activity is desired.

 
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