The present invention relates to the novel derivatives of formula (I) in
which 1
A is, if it is present, a (C1-C6) alkyl, a (C3-C6) alkenyl, a (C3-C6)
alkynyl, a (C3-C7) cycloalkyl or a (C5-C7) cycloalkenyl, R1 is an NR6R7,
(C4-C7) azacycloalkyl, (C5-C7) azacycloalkenyl, (C5-C9) azabicycloalkyl
or (C5-C9) azabicycloalkenyl group; A-R1 is such that the nitrogen of R1
and the nitrogen in the 1-position of the pyrazole are necessarily
separated by at least two carbon atoms, R3 is an H, halogen, OH, SH,
NH.sub.2, ORc, SRc, SORa, SO.sub.2Ra, NHCHO, NRaRb, NHC(O)Ra, NHC(S)Ra or
NHSO.sub.2Ra, R4 is an aryl or heteroaryl; and R5 is an H, halogen,
CF.sub.3, CHF.sub.2, CH.sub.2F, linear or branched (C1-C6) alkyl or
(C3-C7) cycloalkyl to their racemates, enantiomers and diastereoisomers
and to their mixtures, their tautomers and to their pharmaceutically
acceptable salts.
