The subject invention relates to methods for detection of mutations in a PKD
gene using DHPLC. The invention includes the following aspects: identification
of PKD unique sites; design of PKD-specific primers; amplification of PKD-specific
products; and analysis of PCR amplified products by DHPLC. The invention further
relates to compositions such as identified unique sites and PKD-specific primers,
and kits for performing the methods of the invention.
