A method is disclosed for rapid molecular profiling of tissue or other cellular
specimens by placing a donor specimen in an assigned location in a recipient array,
providing copies of the array, and performing a different biological analysis of
each copy. The results of the different biological analyses are compared to determine
if there are correlations between the results of the different biological analyses
at each assigned location. In some embodiments, the specimens may be tissue specimens
from different tumors, which are subjected to multiple parallel molecular (including
genetic and immunological) analyses. The results of the parallel analyses are then
used to detect common molecular characteristics of the genetic disorder type, which
can subsequently be used in the diagnosis or treatment of the disease. The biological
characteristics of the tissue can be correlated with clinical or other information,
to detect characteristics associated with the tissue, such as susceptibility or
resistance to particular types of drug treatment. Other examples of suitable tissues
which can be placed in the matrix include tissue from transgenic or model organisms,
or cellular suspensions (such as cytological preparations or specimens of liquid
malignancies or cell lines).
