Piperazine CCR-3 receptor antagonists

   
   

The invention provides compounds of Formula (I): ##STR1##

wherein: R1-R4, A, L, and X have any of the values defined in the specification that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use, and methods and intermediates useful for preparing them.

 
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> Compounds possessing antibacterial, antifungal or antitumor activity

> Vertical NROM having a storage density of 1 bit per 1F2

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