Disclosed are compounds of the formula:
##STR1##
- or pharmaceutically acceptable salts or pharmaceutically acceptable
solvates thereof,
- wherein R1, R2, R3, X, Q1
and Q2 are defined herein,
- which compounds are ligands for neurokinin receptors, in particular
NK-3 receptors, and are therefor useful in the treatment of a wide range of diseases
or disorders including, but not limited to depression, anxiety, psychosis, obesity,
pain, Parkinson's disease, Alzheimer's disease, neurodegenerative diseases, movement
disorders, respiratory diseases, inflammatory diseases, neuropathy, immune disorders,
migraine, biliary disfunction, and dermatitis.
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