The present invention provides compositions and methods for modulating B-lymphocyte
activation. Nucleic acids encoding proteins and proteins so encoded which are capable
of modulating B-lymphocyte activation are provided. Compositions and methods for
the treatment of disorders related to dysfunction or dysregulation of B-lymphocyte
activation are also provided. Prophylactics and methods for the prevention of such
disorders are also provided. Also provided are compositions and methods for diagnostic
and prognostic determination of such disorders. Further provided are assays for
the identification of bioactive agents capable of modulating B-lymphocyte activation.
