Mutant B-type DNA polymerases exhibiting improved performance in PCR

   
   

The present invention relates to thermostable mutants of B-type DNA polymerases comprising a Y-GG/A amino acid motif between the N-terminal 3'-5'-exonuclease domain and the C-terminal polymerase domain whereas the tyrosine of the Y-GG/A amino acid motif is mutated and whereas these mutant DNA polymerases are suitable for PCR.

Присытствыющий вымысел относит к термостабильным мутантам полимераз ДНАА Б-tipa состоя из motif amino acid Y-GG/A между доменом Н-sterjn4 3'-5'-exonuclease и доменом полимеразы Ч-sterjn4 тогда как тирозин motif amino acid Y-GG/A mutated и тогда как эти полимеразы ДНАА мутанта целесообразны для PCR.

 
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