One aspect of the present invention relates to novel peptidomimetic
compounds. A second aspect of the present invention relates to the use of
the novel peptidomimetic compounds as ligands--agonists or
antagonists--for various cellular receptors, e.g., G-protein-coupled
receptors and opioid receptors, and various cellular ion channels, e.g.,
sodium and calcium. In certain embodiments, compounds of the present
invention preferentially or selectively inhibit sodium or calcium ion
channels. In certain embodiments, compounds of the present invention
preferentially or selectively agonize or antagonize $gm opioid receptors.
In certain embodiments, compounds of the present invention preferentially
or selectively inhibit sodium or calcium ion channels and agonize or
antagonize $gm-opioid receptors.
