Solvent systems

   
   

In a method for making bisphosphonates by reacting a carbonyl compound with a phosphorus halide, the reaction is carried out in a solvent/carrier system which is a mixture of an amine hydrochloride, phosphorous acid and optionally phosphoric acid.

В метод для делать bisphosphonates путем реагировать смесь карбонила с галоидом фосфора, реакция снесена вне в системой solvent/carrier которая будет смесь хлоргидрата амина, фосфористой кислоты и опционно фосфорной кислоты.

 
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