EPOTHILONE SYNTHESIS BUILDING BLOCKS III AND IV: ASYMMETRICALLY SUBSTITUTED ACYLOINS AND ACYLOIN DERIVATIVES, METHODS FOR THEIR PRODUCTION AND METHODS FOR THE PRODUCTION OF EPOTHILONES B, D AND EPOTHILONE DERIVATIVES

   
   

The present invention is directed to novel acyloins, their derivatives, methods for their production and their use for the production of novel epothilones and their derivatives. In addition, the invention is directed to the building blocks for epothilone synthesis, methods for their production and the use of synthetic building blocks for the production of epothilones and their derivatives.

La présente invention est dirigée vers des acyloins de roman, leurs dérivés, des méthodes pour leur production et leur utilisation pour la production des epothilones de roman et de leurs dérivés. En outre, l'invention est dirigée vers les modules pour la synthèse d'epothilone, des méthodes pour leur production et l'utilisation des modules synthétiques pour la production des epothilones et de leurs dérivés.

 
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