Biologically active peptides and compositions, their use

   
   

This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, ##STR1## wherein Y, n, R.sub.1, R.sub.2, R.sub.3, R.sub.6, R.sub.7, R.sub.70, R.sub.71, R.sub.72, R.sub.74, and R.sub.75 are as defined in the specification.

Deze uitvinding heeft op derivaten die van hemiasterlin of Geodiamolide G anti-mitotic activiteiten hebben betrekking en nuttig in het behandelen van kanker. Deze derivaten worden vertegenwoordigd door algemene formule I, ## STR1 ## waarin Y, n, R.sub.1, R.sub.2, R.sub.3, R.sub.6, R.sub.7, R.sub.70, R.sub.71, R.sub.72, R.sub.74, en R.sub.75 zoals die in de specificatie wordt bepaald zijn.

 
Web www.patentalert.com

< Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity

< Cytostatic cerium compounds

> 2-Phenyliminothiazolines, their preparation method and anti-rice blast agent containing the same

> Isoquinolinone potassium channels inhibitors

~ 00169