The present invention relates to the field of metabolic research, in
particular the discovery of compounds effective for reducing body mass
and useful for treating obesity-related diseases and disorders. The
obesity-related diseases or disorders envisioned to be treated by the
methods of the invention include, but are not limited to, hyperlipidemia,
atherosclerosis, insulin resistance, diabetes, and hypertension. In
particular, the invention provides for methods of identifying and using
AGONISTS and ANTAGONISTS of MOXIFIN activity, wherein said activity is
selected from the group consisting of lipid partitioning, lipid
metabolism, and insulin-like activity.
A invenção atual relaciona-se ao campo da pesquisa metabolic, no detalhe a descoberta dos compostos eficazes para reduzir a massa do corpo e úteis para tratar doenças e disorders obesity-relacionados. As doenças ou os disorders obesity-relacionados envisioned para ser tratado pelos métodos da invenção incluem, mas não são limitados a, hyperlipidemia, atherosclerosis, resistência de insulin, diabetes, e hypertension. No detalhe, a invenção fornece para métodos de identificar e de usar os AGONISTS e os ANTAGONISTAS da atividade de MOXIFIN, wherein a atividade dita é selecionada do lipid consistindo do grupo que divide, metabolism de lipid, e insulin-como a atividade.
