Therapies for chronic renal failure

   
   

The present invention provides methods for the treatment, and pharmaceuticals for use in the treatment, of mammalian subjects in, or at risk of chronic renal failure, or at risk of a need for renal replacement therapy. The methods involve the administration of certain proteins of, or based upon, the osteogenic protein/bone morphogenetic protein (OP/BMP) family within the TGF-.beta.superfamily of proteins.

De onderhavige uitvinding verstrekt methodes voor de behandeling, en geneesmiddelen voor gebruik in de behandeling, binnen van zoogdieronderwerpen, of op risico van chronische niermislukking, of op risico van een behoefte aan niervervangingstherapie. De methodes houden het beleid van bepaalde proteïnen van, of gebaseerd op, de osteogenic proteïne in/been morphogenetic eiwit (OP/BMP) familie binnen tgf-.beta.superfamily van proteïnen.

 
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