Process for producing optically active amide from .alpha. .beta.- unsaturated amide derivative in the presence of transition metal complex containing phosphine-phosphorane compound and transition metal

   
   

A novel process for producing an optically active amide excellent in chemical selectivity and enantioselectivity by asymmetric hydrogenation of an .alpha.,.beta.-unsaturated amide and also allowing the reaction to proceed efficiently even when a trace amount of a catalyst is used relative to the substrate as compared with the amount in a conventional process. An optically active amide is produced by asymmetric hydrogenation of an .alpha.,.beta.-unsaturated amide derivative in the presence of a transition metal complex containing a specific phosphine-phosphorane compound.

 
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