Time-resolved fluorescence assay for the detection of multimeric forms of A-beta 1-40

   
   

The present invention provides for a polypeptide aggregation screening assay for the purpose of detecting modulators of polypeptide aggregation, which can provide for new therapies in pathologic states associated with polypeptide aggregation, especially considered is Alzheimer's Disease.

 
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< Alzheimer's disease secretase, APP substrates therefor, and uses therefor

< Pyridazinone inhibitors of fatty acid binding protein and method

> Transgenic mouse assay to determine the effect of A.beta. antibodies and A.beta. Fragments on alzheimer's disease characteristics

> Helical peptidomimetics

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