Immunogenic composition comprising an influenza virus with a temperature sensitive PB2 mutation

   
   

Recombinant PB2 variant influenza viruses, RNA, cDNA and vectors are provided. Also provided are immunogenic compositions containing the variant viruses, methods of producing such viruses and methods for the prophylactic treatment of influenza in humans.

De recombinante PB2 verschillende de griepvirussen, RNA, DNA en vectoren worden verstrekt. Op voorwaarde dat ook immunogene samenstellingen die de verschillende virussen zijn, methodes om dergelijke virussen te produceren en methodes voor de profylactische behandeling van griep in mensen bevatten.

 
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