Indolyl-urea derivatives of thienopyridines useful as antiangiogenic agents, and methods for their use

   
   

The invention relates to compounds represented by the formula I ##STR1## and to prodrugs thereof, pharmaceutically acceptable salts or solvates of said compounds or said prodrugs, wherein X, R.sup.1 and R.sup.11 are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.

A invenção relaciona-se aos compostos representados pelo ## do ## STR1 da fórmula I e aos prodrugs disso, pharmaceutically sais aceitáveis ou solvates de compostos ditos ou de prodrugs ditos, wherein X, R.sup.1 e R.sup.11 são como definidos nisto. A invenção relaciona-se também às composições pharmaceutical que contêm os compostos da fórmula I e aos métodos de tratar disorders hyperproliferative em um mamífero administrando os compostos da fórmula I.

 
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