Antibodies to receptor protein tyrosine kinases

   
   

The protein tyrosine kinase receptors, designated Rse and HPTK6, have been purified from human and/or murine cell tissues. Rse and HPTK6 have been cloned from a cDNA library of a human liver carcinoma cell line (i.e., Hep 3B) using PCR amplification. Provided herein are nucleic acid sequences encoding Rse and HPTK6 useful as diagnostics and in the recombinant preparation of Rse and HPTK6. Rse and HPTK6 are used in the preparation and purification of antibodies thereto and in diagnostic assays.

Os receptors do kinase do tyrosine da proteína, designados Rse e HPTK6, purified dos tecidos humanos e/ou murine da pilha. Rse e HPTK6 cloned de uma biblioteca do DNA de uma linha humana da pilha do carcinoma do fígado (isto é, 3B hep) usando o amplification de PCR. Desde que seja nisto nucleic o ácido arranja em seqüência Rse e HPTK6 codificando úteis como o diagnóstico e na preparação recombinant de Rse e de HPTK6. Rse e HPTK6 são usados na preparação e no purification dos antibodies a isso e em assays diagnósticos.

 
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