The present invention relates to a method for identifying unknown
molecular interactions within biological networks based on
representations of molecules as sets of conserved features. Such
molecules include but are not limited to proteins and nucleic acid
molecules which can be represented as collections of conserved features,
such as domains and motifs in proteins. The method of the invention
comprises computing the attraction probabilities between molecules
followed by calculation of the probability of a biological network. The
method of the invention can be applied across species, where interaction
data from one, or several species, can be used to infer molecular
interactions between molecules acting within or between organisms. The
method of the present invention may be used to identify molecular
interactions which can serve as drug screening targets.
