Method for producing a polynucleotide library in vitro by mismatch repair of heteroduplexes

   
   

A method for making polynucleotide libraries that comprise new recombined polynucleotides by using mismatch repair enzymes or proteins to shuffle at least two variants of the same polynucleotide or at least two homologous polynucleotides through a Recombinatorial Chain Reaction, RCR.

Un metodo per fare le biblioteche che contengono i nuovi polynucleotides ricombinati usando gli enzimi o le proteine di riparazione del disadattamento per mescolareare almeno due varianti dello stesso polynucleotide o almeno di due polynucleotides omologhi con una reazione a catena di Recombinatorial, RCR di polynucleotide.

 
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