Pharmaceutically active compounds

   
   

Compounds of general formula I: ##STR1## or pharmaceutically or veterinarily acceptable salts, solvates, polymorphs or pro-drugs thereof wherein: wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, X and A have the meanings given herein which are useful in the curative and prophylactic treatment of a medical condition for which inhibition of a cyclic guanosine 3',5'-monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.

Compostos da fórmula geral I: ## do ## STR1 ou sais, solvates, polymorphs ou pro-drugs pharmaceutically ou veterinarily aceitáveis disso wherein: wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, X e A têm os meanings dados nisto que são úteis no tratamento curative e prophylactic de uma condição médica para que a inibição de um guanosine cíclico 3', phosphodiesterase 5'-monophosphate (por exemplo GMP PDE5) é desejada.

 
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