Disclosed are controlled-release mucoadhesive pharmaceutical compositions
for the oral administration of furosemide. This composition comprises a
multiplicity of microgranules of lipophilic material which are coated with
a mucoadhesive coating. This invention reduced or eliminates the diuresis
peak and reduces inter-subject response variability which normally
accompany conventional treatment with this drug.
São divulgados controlado-liberam composições pharmaceutical mucoadhesive para a administração oral do furosemide. Esta composição compreende um multiplicity dos microgranules do material lipophilic que são revestidos com um revestimento mucoadhesive. Esta invenção reduziu ou elimina o pico do diuresis e reduz o variability da resposta do inter-assunto que acompanham normalmente o tratamento convencional com esta droga.
