14815, a human kinase family member and uses therefor

   
   

The invention provides isolated nucleic acids molecules, designated 14815 nucleic acid molecules, which encode novel kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 14815 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 14815 gene has been introduced or disrupted. The invention still further provides isolated 14815 proteins, fusion proteins, antigenic peptides and anti-14815 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

De uitvinding verstrekt geïsoleerde nucleic zurenmolecules, aangewezen 14815 nucleic zuurmolecules, die de nieuwe leden van de kinasefamilie coderen. De uitvinding verstrekt antisense nucleic zuurmolecules, recombinante uitdrukkingsvectoren 14815 nucleic zuurmolecules bevatten, ook gastheercellen waarin de uitdrukkingsvectoren zijn geïntroduceerd, en nonhuman transgenic dieren die waarin een gen 14815 is geïntroduceerd of onderbroken. De uitvinding verstrekt steeds verder geïsoleerd 14815 proteïnen, fusieproteïnen, antigenic peptides en anti-14815 antilichamen. De kenmerkende en therapeutische methodes die samenstellingen van de uitvinding gebruiken worden ook verstrekt.

 
Web www.patentalert.com

< Cyclic hydroxamic acids as inhibitors of matrix metalloproteinases and/or TNF- .alpha. converting enzyme (TACE)

< Cardiovascular system associated protein kinase 2 (CSAPK-2) antibodies

> Fiber-reinforced, porous, biodegradable implant device

> Cathepsin V-like polypeptides

~ 00119