Use of parapox PP30 protein to modify immune responses to administered antigens

   
   

The Parapox B2L virus envelope protein is used as an adjuvant to enhance a subject's response to an administered antigen. Both antibody and cellular immune responses can be modified. B2L protein is particularly useful as an adjuvant for poorly immunogenic tumor vaccines and subunit vaccines, such as those useful for preventing and/or treating flu, tuberculosis, respiratory syncytial virus, anthrax and HIV.

La proteína del sobre del virus de Parapox B2L se utiliza como coadyuvante para realzar la respuesta de un tema a un antígeno administrado. El anticuerpo y las inmunorespuestas celulares pueden ser modificados. La proteína de B2L es particularmente útil como coadyuvante para las vacunas mal inmunogenéticas del tumor y las vacunas de la subunidad, tales como ésos útiles para prevenir y/o tratar gripe, tuberculosis, el virus syncytial respiratorio, el ántrax y el VIH.

 
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