(-)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake inhibitor

   
   

The present invention relates to (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane and pharmaceutically acceptable salts thereof, compositions comprising (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or a pharmaceutically acceptable salt thereof, and methods for treating or preventing a disorder alleviated by inhibiting dopamine reuptake. In one embodiment, the disorder is attention-deficit disorder, depression, obesity, Parkinson's disease, a tic disorder, or an addictive disorder. The (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane or pharmaceutically acceptable salt thereof is preferably substantially free of its corresponding (+)-enantiomer.

A invenção atual relaciona-se a (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane e pharmaceutically sais aceitáveis disso, compreender das composições (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane ou um sal pharmaceutically aceitável disso, e métodos para tratar ou impedir um disorder aliviado inibindo o reuptake do dopamine. Em uma incorporação, o disorder é disorder do atenção-deficit, depression, obesity, doença de Parkinson, um disorder tic, ou um disorder addictive. (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane ou pharmaceutically sal aceitável disso está preferivelmente substancialmente livre de seu corresponder (+)-enantiomer.

 
Web www.patentalert.com

< Venlafaxine besylate

< Benzofuran derivatives

> Controlled release formulations using intelligent polymers

> Fused heterocyclic compounds

~ 00107