Disclosed herein are ester-bond containing tea polyphenols that has a
susceptibility to nucleophilic attack, their analogs and pharmaceutically
acceptable salts, method for inhibiting proteasomal chymotrypsin-like
activity in vivo and in vitro, methods for cancer treatment with
tea-derived polyphenols, such as EGCG, ECG, GCG, or CG, as well as
pharmaceutical compositions comprising the same.
