The present invention relates to prognostic methods which are useful in
medicine, particularly cancer chemotherapy. The object of the invention to
provide a method for assessing GST-pi expression levels in fixed or fixed
and paraffin embedded tissues and prognosticate the probable resistance or
sensitivity of a patient's tumor to treatment with platinum-based
therapies by examination of the amount of GST-pi mRNA in a patient's tumor
cells and comparing it to a predetermined threshold expression level. More
specifically, the invention provides to oligonucleotide primer pair GST-pi
and methods comprising their use for detecting levels of GST-pi mRNA.
