The present invention relates to 5-heterocyclo-pyrazoles of the formula I: ##STR1## wherein ring W, m, n, and R.sup.1 through R.sup.5 are as defined in the specification, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the invention are useful in the treatment or alleviation of inflammation and other inflammation associated disorders, such as arthritis, colon cancer, and Alzheimer's disease in mammals, preferably humans, dogs, cats and livestock animals.

A invenção atual relaciona-se a 5-heterocyclo-pyrazoles da fórmula I: ## do ## STR1 wherein o anel W, m, n, e R.sup.1 com R.sup.5 é como definido na especificação, às composições pharmaceutical que contêm as e a seu uso medicinal. Os compostos da invenção são úteis no tratamento ou no alleviation do inflammation e de outros disorders associados inflammation, tais como o arthritis, o cancer de dois pontos, e a doença de Alzheimer nos mamíferos, preferivelmente nos seres humanos, nos cães, nos gatos e nos animais dos animais domésticos.

 
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