Cell-based gene transfer is effected by administering transfected cells
containing an expressible transgene into the pulmonary system of a
patient, where the cells express and secrete expression products of the
transgene directly into the pulmonary system. Also provided is the use of
angiogenic factors in treatment of pulmonary hypertension.
Transferência cell-based do gene é efetuada administrando transfected as pilhas que contêm um transgene expressible no sistema pulmonary de um paciente, onde as pilhas expressem e secrete produtos da expressão do transgene diretamente no sistema pulmonary. É fornecido também o uso de fatores angiogenic no tratamento do hypertension pulmonary.