Novel pharmaceutically/cosmetically-active aromatic polyenic compounds have the structural formula (I): ##STR1## and are useful for the treatment of a wide variety of disease states, whether human or veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and ophthalmological disorders, as well as for the treatment of mammalian skin and hair conditions/disorders.

Os compostos polyenic aromatic da novela pharmaceutically/cosmetically-active têm a fórmula estrutural (i): ## do ## STR1 e são útil para o tratamento de uma variedade larga de estados da doença, se o ser humano ou o veterinário, para o exemplo dermatological, rheumatic, respiratory, cardiovascular, o osso e disorders ophthalmological, as.well.as para o tratamento da pele e do cabelo mammalian conditions/disorders.