The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligands NL1, NL5 and NL8, the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules.

Le preoccupazioni attuali di invenzione hanno isolato le molecole dell'acido nucleico che mettono i ligands in codice NL1, NL5 e NL8, le proteine del LEGAME del romanzo messe da tali molecole dell'acido nucleico, come pure i metodi ed i mezzi per fare ed usando tali molecole della proteina e dell'acido nucleico.

 
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