Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.

 
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> Disalt inhibitors of IL-12 production

> Antibodies to interleukin-like epithelial-mesenchymal transition inducer (ILEI)
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