The invention provides an in silico model for determining a S. cerevisiae
physiological function. The model includes a data structure relating a
plurality of S. cerevisiae reactants to a plurality of S. cerevisiae
reactions, a constraint set for the plurality of S. cerevisiae reactions,
and commands for determining a distribution of flux through the reactions
that is predictive of a S. cerevisiae physiological function. A model of
the invention can further include a gene database containing information
characterizing the associated gene or genes. The invention further
provides methods for making an in silico S. cerevisiae model and methods
for determining a S. cerevisiae physiological function using a model of
the invention.
