An apparatus and method of use are disclosed for rapidly and repeatedly cleaning a skin area during tattooing or body piercing. The apparatus includes a plurality of serially dispensable, antiseptic wet wipes pre-moistened with "tincture of green soap" solution. It eliminates any need to dilute a concentrated green soap solution or clean a spray bottle, and allows a tattoo artist to quickly and conveniently obtain and use a wet wipe of the invention in a controlled and consistent manner using only one hand, thereby avoiding interruption of the procedure and contamination of the wet wipe. The wet wipes and/or green soap can be medically approved, and the wipes can be disposable and/or made from non-woven paper, with a preferable size of 19.5 by 17.0 centimeters. The wet wipes can be interleaved or formed in a continuous sheet with perforated separations, and can be folded, or configured in a roll.