A guided process framework includes a process engine, one or more data stores, and one or more user interfaces configured to communicate with the process engine. A user can access a given process instance through any appropriately configured user interface, which contacts the process engine, and which in turn contacts/consults definitions for one or more guided processes at a data store. If the user finishes only part of a given process instance, the process engine can save state corresponding to the progress in the data store. A user can continue work on the process instance through a different user interface (or at a different computer system) by contacting the process engine through the different user interface, and receiving rendering information configured for the different user interface. Thus, the user can stop and start work on a process however desired, and with whatever tools are available at any given time.