A method of programming a programmable logic device (PLD), in accordance with an embodiment, includes receiving trigger unit information of a logic analyzer via a software interface for monitoring internal PLD signals and providing trigger unit output signals based on the internal PLD signals for the corresponding trigger units; and receiving trigger expression information of the logic analyzer via the software interface as a text string of logic operators and operands, wherein the operands represent the trigger unit output signals. The method may further include generating configuration data based on the trigger unit information and the trigger expression information; and providing the configuration data to the PLD, wherein a trigger expression based on the trigger expression information is stored within memory of the PLD.