Substituted disulfonamide compounds corresponding to formula I:
##STR00001##
In which R.sup.1, R.sup.2, R.sup.3, R.sup.4a, R.sup.4b, R.sup.5a,
R.sup.5b, R.sup.8, R.sup.9a, R.sup.9b, R.sup.10, R.sup.11, a, b, s, t and
A have defined meanings, pharmaceutical compositions containing one or
more such compounds, processes for preparing such compounds, and a method
of using such compounds for the treatment or inhibition of pain and/or
other conditions mediated by the bradykinin receptor 1 (BR1).
