A method for performing memory diagnostics using a programmable diagnostic memory module provides enhanced testability of memory controller and memory subsystem design. The programmable diagnostic memory module includes an interface for communicating with an external diagnostic system, and the interface is used to transfer commands to the memory module to alter various behaviors of the memory module. The altered behaviors may be changing data streams that are written to the memory module to simulate errors, altering the timing and/or loading of the memory module signals, downloading programs for execution by a processor core within the memory module, changing driver strengths of output signals of the memory module, and manipulating in an analog domain, signals at terminals of the memory module such as injecting noise on power supply connections to the memory module. The memory module may emulate multiple selectable memory module types, and may include a complete storage array to provide standard memory module operation.