A computer implemented method, system and computer program product for automatically generating SIMD code. The method begins by analyzing data to be accessed by a targeted loop including at least one statement, where each statement has at least one memory reference, to determine if memory accesses are safe. If memory accesses are safe, the targeted loop is simdized. If not safe, it is determined if a scheme can be applied in which safety need not be guaranteed. If such a scheme can be applied, the targeted loop is simdized according to the scheme. If such a scheme cannot be applied, it is determined if padding is appropriate. If padding is appropriate, the data is padded and the targeted loop is simdized. If padding is not appropriate, non-simdized code is generated based on the targeted loop for handling boundary conditions, the targeted loop is simdized and combined with the non-simdized code.