The present invention relates to compositions and methods for the delivery of therapeutic proteins to the CNS using recombinant AAV vectors. More specifically, the invention relates to compositions and methods for delivering proteins into the cerebrospinal fluid of mammalian subjects through peripheral administration of AAV vectors. The invention may be used to treat various disorders of the central nervous system, including degenerative diseases and motor neuron diseases.

 
Web www.patentalert.com

< MULTIPLE EXON SKIPPING COMPOSITIONS FOR DMD

< METHODS AND IMMUNE MODULATOR NUCLEIC ACID COMPOSITIONS FOR PREVENTING AND TREATING DISEASE

> DNA-PKCS MODULATES ENERGY REGULATION AND BRAIN FUNCTION

> USE OF ROSMARINIC ACID IN MANUFACTURE OF MEDICAMENTS FOR TREATING OR PREVENTING HEPATIC AND RENAL DISEASES

~ 00610