It is an object of the present invention to provide a hollow fiber membrane module which maximizes the efficiency of removing scale-like contaminants generated at the water treatment using hollow fiber membranes, and a method of manufacturing the same. The hollow fiber membrane module includes hollow fiber membranes for making water treatment due to the pressure difference, and a collector fixing the hollow fiber membranes in bundle. A treated-water tube is extended to the inside of the collector, and communicated with the inner passage of the hollow fiber membranes to deliver the water treated through the hollow fiber membranes. A diffuser is installed at the collector to diffuse bubbles to the hollow fiber membranes. An air tube is extended to the collector, and connected to the diffuser to feed air. Dividers are installed over the collector to partition the hollow fiber membranes into a plurality of bundles.